Try to disable, if possible, the Disable in Information Governance Catalog (IGC) the capture of lineage for those objects for which lineage is not required. See https://www.ibm.com/support/knowledgecenter/SSZJPZ_11.7.0/com.ibm.swg.im.iis.mdwb.doc/topics/t_configAssetsForBusinessLineage.html.
Improve performance of DB2 XMETA (RUNSTATS and REORG on tables). See https://www.ibm.com/support/pages/node/607015.
Increase WAS heap size. See https://www.ibm.com/docs/en/iis/11.5?topic=catalog-computing-allocating-memory-information-governance.
Manage operational metadata. If you only need operational metadata from the last thirty days remove metadata older than thirty days using istool. See https://www.ibm.com/docs/en/iis/11.7?topic=assets-workbench-purgeomd.

Conclusion

This list of possible causes is not exhaustive, and is only provided to provide starting points for your own investigation of the issue.

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